Cinquin Lab

Molecular processes

Understanding the somitogenesis clock: what’s missing?

Cinquin O. Mech. Dev. 124(7-8), pp501-517 (2007) Abstract The segmentation of vertebrate embryos depends on a complex genetic network that generates highly dynamic gene expression. Many of the elements of the network have been identified, but their interaction and their…

High-dimensional switches and the modeling of cellular differentiation

Cinquin O., Demongeot J., J. Theor. Biol. 233(3), pp391-411 (2005) Abstract Many genes have been identified as driving cellular differentiation, but because of their complex interactions, the understanding of their collective behaviour requires mathematical modelling. Intriguingly, it has been observed…